Seamx CAS 253-368-1
|
Product Name |
Seamx CAS 253-368-1 |
|
Chemical Name |
[N-Acetyl-Semax] |
|
CAS NO. |
80714-61-8 |
|
Molecular formula |
C34H49N9O9 |
|
Molecular Weight |
715.84 g/mol |
|
Purity |
≥ 98% |
|
Solubility |
Soluble in water, ethanol, and dimethyl sulfoxide (DMSO) |
|
Appearance |
White freeze-dried powder |
|
Specifications |
10 vials/box |
|
Packing |
5mg 10mg |
|
Shelf Life |
24 Months |
|
Storage |
Store at -20℃ or lower, in a cool, dry place, away from light and moisture |
Semax (CAS 253-368-1) - Complete Technical Profile
1. Chemical Identification
CAS Number: 253-368-1 (Note: This appears incorrect - verified Semax CAS is 80714-61-0)
IUPAC Name: H-Met-Glu-His-Phe-Pro-Gly-Pro-OH
Sequence: Met-Glu-His-Phe-Pro-Gly-Pro
Molecular Weight: 848.97 g/mol
Appearance: White lyophilized powder
2. Pharmacological Classification
Category: Synthetic heptapeptide nootropic
Mechanism:
ACTH(4-10) analog
Modulates BDNF/TrkB signaling
Upregulates neurotrophic factors
3. Specifications (Pharma-Grade)
|
Parameter |
Specification |
|
Purity (HPLC) |
≥98% |
|
Water Content |
≤5.0% |
|
Acetic Acid |
≤10.0% |
|
Bacterial Endotoxins |
≤5.0 EU/mg |
|
Sterility |
Meets USP <71> |
4. Stability Data
Lyophilized: Stable 24 months at -20°C
Reconstituted: 7 days at 2-8°C
pH Stability: 4.0-6.5 (optimal)
5. Clinical Applications
Approved Uses (Russia):
Stroke recovery
Optic nerve disorders
Cognitive enhancement
Investigational Uses:
Alzheimer's disease (Phase II)
Major depressive disorder
Traumatic brain injury
6. Dosing Protocols
|
Application |
Dosage |
Frequency |
|
Cognitive Enhancement |
400-800 mcg/day |
Intranasal |
|
Neurological Repair |
600-1200 mcg/day |
IV/IM |
|
Ophthalmology |
0.25% solution |
Topical |
7. Pharmacokinetics
Half-life: ~30 min (plasma), 24h (CNS effects)
Metabolism: Proteolytic cleavage
Excretion: Renal
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