Semaglutide-2mg

Product Name	Semaglutide-2mg
Appearance	Lyophilized powder
Purity	≥99.0%
Storage method	freeze-drying at -20℃ and storage away from light
Note	For research purposes only, not for human use

Semaglutide 2 mg is a high-dose formulation of the glucagon-like peptide-1 (GLP-1) receptor agonist used primarily for:

1. Approved Uses

Type 2 Diabetes (Ozempic® / Rybelsus®)

Ozempic® (injection): 2 mg is the highest weekly dose for improving blood sugar control (along with diet and exercise).

Rybelsus® (oral tablet): The highest dose is 14 mg daily; 2 mg is a lower dose in the titration schedule.

Chronic Weight Management (Wegovy®)

Wegovy® (injection): 2.4 mg is the maintenance dose (not 2 mg), taken weekly for obesity or overweight with weight-related conditions.

2. Key Considerations

Dosing Schedule: Typically started at a lower dose (e.g., 0.25 mg/week for Ozempic) to reduce side effects (nausea, vomiting).

Effectiveness:

Diabetes: Lowers HbA1c by ~1-1.5% at higher doses.

Weight Loss: In trials, Wegovy® (2.4 mg) led to ~15% weight loss over 68 weeks.

Side Effects: GI issues (nausea, diarrhea), potential pancreatitis, gallbladder disease, and rare thyroid tumor risk (contraindicated in personal/family history of medullary thyroid cancer or MEN2).